diff --git a/core/org.eclipse.cdt.core.tests/parser/org/eclipse/cdt/core/parser/tests/ast2/AST2TemplateTests.java b/core/org.eclipse.cdt.core.tests/parser/org/eclipse/cdt/core/parser/tests/ast2/AST2TemplateTests.java
index a8cedf674bc..8e258b4da25 100644
--- a/core/org.eclipse.cdt.core.tests/parser/org/eclipse/cdt/core/parser/tests/ast2/AST2TemplateTests.java
+++ b/core/org.eclipse.cdt.core.tests/parser/org/eclipse/cdt/core/parser/tests/ast2/AST2TemplateTests.java
@@ -7085,6 +7085,22 @@ public class AST2TemplateTests extends AST2TestBase {
 		parseAndCheckBindings();
 	}
 
+	//	template<typename T>
+	//	struct A {};
+	//
+	//	template<typename T>
+	//	using B = A<T>;
+	//
+	//	template<typename T>
+	//	void f(B<T>* p);
+	//
+	//	void test(A<int>* c) {
+	//	  f(c);
+	//	}
+	public void testAliasTemplate_416280() throws Exception {
+		parseAndCheckBindings();
+	}
+
 	//	template<typename U>
 	//	struct A {
 	//	  typedef U type1;
diff --git a/core/org.eclipse.cdt.core/parser/org/eclipse/cdt/internal/core/dom/parser/cpp/semantics/TemplateArgumentDeduction.java b/core/org.eclipse.cdt.core/parser/org/eclipse/cdt/internal/core/dom/parser/cpp/semantics/TemplateArgumentDeduction.java
index fa1f084246c..6e1104260a8 100644
--- a/core/org.eclipse.cdt.core/parser/org/eclipse/cdt/internal/core/dom/parser/cpp/semantics/TemplateArgumentDeduction.java
+++ b/core/org.eclipse.cdt.core/parser/org/eclipse/cdt/internal/core/dom/parser/cpp/semantics/TemplateArgumentDeduction.java
@@ -292,6 +292,9 @@ public class TemplateArgumentDeduction {
 						}
 					}
 				}
+				while (pcheck instanceof ITypedef)
+					pcheck = ((ITypedef) pcheck).getType();
+
 				if (pcheck instanceof ICPPTemplateInstance && argcheck instanceof ICPPClassType) {
 					ICPPTemplateInstance pInst = (ICPPTemplateInstance) pcheck;
 					ICPPClassTemplate pTemplate= getPrimaryTemplate(pInst);
@@ -830,6 +833,8 @@ public class TemplateArgumentDeduction {
 			IType argumentTypeBeforeTypedefResolution = a;
 			while (a instanceof ITypedef)
 				a = ((ITypedef) a).getType();
+			while (p instanceof ITypedef)
+				p = ((ITypedef) p).getType();
 			if (p instanceof IBasicType) {
 				return p.isSameType(a);
 			} else if (p instanceof ICPPPointerToMemberType) {