diff --git a/debug/org.eclipse.cdt.debug.ui/src/org/eclipse/cdt/debug/internal/ui/disassembly/dsf/IDisassemblyBackend.java b/debug/org.eclipse.cdt.debug.ui/src/org/eclipse/cdt/debug/internal/ui/disassembly/dsf/IDisassemblyBackend.java
index e2aec17959e..dd4b8db4f4f 100644
--- a/debug/org.eclipse.cdt.debug.ui/src/org/eclipse/cdt/debug/internal/ui/disassembly/dsf/IDisassemblyBackend.java
+++ b/debug/org.eclipse.cdt.debug.ui/src/org/eclipse/cdt/debug/internal/ui/disassembly/dsf/IDisassemblyBackend.java
@@ -218,4 +218,10 @@ public interface IDisassemblyBackend {
 	 * @return the last know address, -1 if unknown
 	 */
 	BigInteger getLastKnownAddress();
+
+	/**
+	 * Requests that the backend clear any caches that it has so that refresh operations obtain fresh data.
+	 */
+	default void clearCaches() {
+	}
 }
diff --git a/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyBackendDsf.java b/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyBackendDsf.java
index 90af02becfa..b15e2731a92 100644
--- a/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyBackendDsf.java
+++ b/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyBackendDsf.java
@@ -25,6 +25,7 @@ import static org.eclipse.cdt.debug.internal.ui.disassembly.dsf.DisassemblyUtils
 
 import java.math.BigInteger;
 import java.text.MessageFormat;
+import java.util.List;
 import java.util.concurrent.ExecutionException;
 import java.util.concurrent.RejectedExecutionException;
 import java.util.concurrent.TimeUnit;
@@ -45,6 +46,7 @@ import org.eclipse.cdt.dsf.concurrent.ImmediateDataRequestMonitor;
 import org.eclipse.cdt.dsf.concurrent.Query;
 import org.eclipse.cdt.dsf.datamodel.DMContexts;
 import org.eclipse.cdt.dsf.datamodel.IDMContext;
+import org.eclipse.cdt.dsf.debug.service.ICachingService;
 import org.eclipse.cdt.dsf.debug.service.IDisassembly;
 import org.eclipse.cdt.dsf.debug.service.IDisassembly.IDisassemblyDMContext;
 import org.eclipse.cdt.dsf.debug.service.IDisassembly2;
@@ -1307,4 +1309,23 @@ public class DisassemblyBackendDsf extends AbstractDisassemblyBackend implements
 	protected void handleError(IStatus status) {
 		DsfUIPlugin.log(status);
 	}
+
+	@Override
+	public void clearCaches() {
+		final DsfExecutor executor = getSession().getExecutor();
+		executor.execute(new DsfRunnable() {
+			@Override
+			public void run() {
+				List.of(IStack.class, IDisassembly.class, IExpressions.class, IRunControl.class, IRegisters.class,
+						ISourceLookup.class).forEach((clazz) -> {
+							Object o = getService(clazz);
+							if (o instanceof ICachingService) {
+								ICachingService cs = (ICachingService) o;
+								cs.flushCache(getExecutionDMContext());
+							}
+						});
+			}
+		});
+
+	}
 }
diff --git a/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyPart.java b/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyPart.java
index 5f0fcdf2a68..58e1072791b 100644
--- a/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyPart.java
+++ b/dsf/org.eclipse.cdt.dsf.ui/src/org/eclipse/cdt/dsf/debug/internal/ui/disassembly/DisassemblyPart.java
@@ -3277,9 +3277,9 @@ public abstract class DisassemblyPart extends WorkbenchPart
 
 	@Override
 	public void refresh() {
+		fBackend.clearCaches();
 		asyncExec(() -> {
-			fPCLastAddress = getTopAddress();
-			refreshView(10);
+			updatePC(PC_UNKNOWN);
 		});
 	}
 }